osteoporosis-studies.com | Osteoporosis–Studies | Studies on supplements, diet, drugs, and other treatments for bone

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Title	Osteoporosis–Studies \| Studies on supplements, diet, drugs, and other treatments for bone
Description	Osteoporosis–Studies Studies on supplements, diet, drugs, and other treatments for bone strength Menu Home About Glossary Disclaimer Contact Uridine Triph
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osteoporosis-studies.com Valuation

US$955,743

Last updated: 2023-05-16 04:02:02

osteoporosis-studies.com has Semrush global rank of 11,074,435. osteoporosis-studies.com has an estimated worth of US$ 955,743, based on its estimated Ads revenue. osteoporosis-studies.com receives approximately 110,278 unique visitors each day. Its web server is located in United States, with IP address 64.90.44.230. According to SiteAdvisor, osteoporosis-studies.com is safe to visit.

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Daily Unique Visitors	7,352
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Osteoporosis–Studies Studies on supplements, diet, drugs, and other treatments for bone strength Menu Home About Glossary Disclaimer Contact Uridine Triphosphate Inhibits Bone Growth in Rat Cells In Vitro Leave a reply --> Abstract Osteoblast responses to nucleotides increase during differentiation. Accumulating evidence suggests that extracellular nucleotides, signaling through P2 receptors, play a role in modulating bone cell function. ATP and ADP stimulate osteoclastic resorption, while ATP and UTP are powerful inhibitors of bone formation by osteoblasts. We investigated changes in the expression of P2 receptors with cell differentiation in primary osteoblast cultures. Rat calvarial osteoblasts, cultured for up to 10 days, were loaded with the intracellular Ca(2+)-sensing fluorophore, Fluo-4 AM, and a fluorescence imaging plate reader was used to measure responses to nucleotide agonists. Peak responses occurred within 20 s and were evoked by ATP or UTP at concentrations as low

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